| Title | URL | Synopsis |
|---|---|---|
| "A Functional Role for the Conformationally Mobile Amino Acid Phenylalanine 223 in the Reaction of Methylenetetrahydrofolate Reductase from E. coli" | Lee, M.N., Takawira, D., Nikolova, A.P., Ballou, D.P., Furtado, V.C, Phung, N.L., Still, B.R., Thorstad, M.K., Tanner, J.J., and Trimmer, E.E. 2009. Biochemistry, 48, 7673-7685. | |
| "Aspartate 120 of Escherichia coli Methylenetetrahydrofolate Reductase: Evidence for Major Roles in Folate Binding and in Catalysis, Minor Role in Flavin Reactivity" | Trimmer, E.E., Ballou, D.P., Galloway, L.J., Scannell, S.A., Brinker, D.R, and Casas, K.R. 2005. Biochemistry, 44, 6809-6822. | |
| "Studies of the Mechanisms of Bacterial and Mammalian Methylenetetrahydrofolate Reductases" | Ballou, D.P., Yamada, K., Pejchal, R., Ludwig, M.L., Matthews, R.G., Trimmer, E.E. 2002. "Flavins and Flavoproteins 2002," (R.N. Perham ed.), pp. 13-22. | |
| "Methylenetetra-hydrofolate Reductase from Escherichia coli: Elucidation of the Kinetic Mechanism by Steady-State and Rapid-Reaction Studies" | Trimmer, E.E., Ballou, D.P., Matthews, R.G. 2001. Biochemistry, 40, 6205-6215. | |
| "Folate Activation and Catalysis Methylenetetrahydrofolate Reductase from Escherichia coli: Roles for Aspartate 120 and Glutamate 28" | Trimmer, E.E., Ballou, D.P., Ludwig, M.L., Matthews, R.G. 2001. Biochemistry, 40, 6216-6226. | |
| "Purification and Properties of NADH-dependent 5,10-Methylenetetrahydrofolate Reductase (MetF) from Escherichia coli" | Sheppard, C.A., Trimmer, E.E., Matthews, R.G. 1998. J. Bacteriology, 181, 718-725. |
Professor Trimmer is interested in the structure and mechanism of enzymes. Her research has focused on enzymes that perform oxidation/reduction reactions using the coenzyme flavin. She is investigating how the protein environment influences the chemical reactivity of the flavin. Trimmer Summer 2012 Research Description
